Basal ganglia circuits changes in Parkinson’s disease patients Functional changes in basal ganglia circuitry are responsible for the major clinical features of Parkinson’s disease (PD) Current models of basal ganglia circuitry can only partially explain the cardinal symptoms in PD
The organization of the basal ganglia functional connectivity network . . . The motor symptoms in Parkinson's disease (PD) have been linked to changes in the excitatory inhibitory interactions of centers involved in the cortical-subcortical closed-loop circuits which connect basal ganglia (BG) and the brain cortex
Interrogating basal ganglia circuit function in people with Parkinson’s . . . The dichotomy between the hypo- versus hyperkinetic nature of Parkinson’s disease (PD) and dystonia, respectively, is thought to be reflected in the underlying basal ganglia pathophysiology In this study, we investigated differences in globus